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A molecular biologist, Ingram was born in Germany and studied in England. In 1952, while studying protein chemistry -- particularly the genetics of hemoglobin -- at the Cavendish Laboratory at Cambridge, Ingram discovered that a simple mutation was the cause of sickle cell anemia, a serious blood disease. That discovery led to more work which found many other diseases, from hemophilia to cystic fibrosis, are similarly caused by single-gene mutations. The discovery was "one of the absolutely seminal discoveries in the history of molecular biology," said Graham C. Walker, a biology professor at the Massachusetts Institute of Technology, where Ingram went to teach in 1958. Ingram never retired from MIT: in recent years, he had been working on researching Alzheimer's disease. "He was a dyed-in-the-wool, inveterate experimentalist," Walker said. "He was going at full speed right up until the end." Dr. Ingram died August 17 after being injured in a fall. He was 82. From This is True for 20 August 2006 Suggestions for further reading:
 By: Bruce AlbertsAlexander JohnsonJulian LewisMartin RaffKeith RobertsPeter Walter List Price: $142.00 Amazon Price: $110.57 Editorial Review: For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter). The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as pdf files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and -they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint® presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies?animations, videos, and molecular models?all with voiceover narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology. * There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.  By: Hervé This List Price: $29.95 Amazon Price: $19.77 Editorial Review: Hervé This (pronounced "Teess") is an internationally renowned chemist, a popular French television personality, a bestselling cookbook author, a longtime collaborator with the famed French chef Pierre Gagnaire, and the only person to hold a doctorate in molecular gastronomy, a cutting-edge field he pioneered. Bringing the instruments and experimental techniques of the laboratory into the kitchen, This uses recent research in the chemistry, physics, and biology of food to challenge traditional ideas about cooking and eating. What he discovers will entertain, instruct, and intrigue cooks, gourmets, and scientists alike. Molecular Gastronomy, This's first work to appear in English, is filled with practical tips, provocative suggestions, and penetrating insights. This begins by reexamining and debunking a variety of time-honored rules and dictums about cooking and presents new and improved ways of preparing a variety of dishes from quiches and quenelles to steak and hard-boiled eggs. He goes on to discuss the physiology of flavor and explores how the brain perceives tastes, how chewing affects food, and how the tongue reacts to various stimuli. Examining the molecular properties of bread, ham, foie gras, and champagne, the book analyzes what happens as they are baked, cured, cooked, and chilled. Looking to the future, This imagines new cooking methods and proposes novel dishes. A chocolate mousse without eggs? A flourless chocolate cake baked in the microwave? Molecular Gastronomy explains how to make them. This also shows us how to cook perfect French fries, why a soufflé rises and falls, how long to cool champagne, when to season a steak, the right way to cook pasta, how the shape of a wine glass affects the taste of wine, why chocolate turns white, and how salt modifies tastes.  By: Michael J. Behe List Price: $15.00 Amazon Price: $10.20 Editorial Review: The groundbreaking, "seminal work" (Time) on intelligent design that dares to ask, was Darwin wrong? In 1996, Darwin's Black Box helped to launch the intelligent design movement: the argument that nature exhibits evidence of design, beyond Darwinian randomness. It sparked a national debate on evolution, which continues to intensify across the country. From one end of the spectrum to the other, Darwin's Black Box has established itself as the key intelligent design text -- the one argument that must be addressed in order to determine whether Darwinian evolution is sufficient to explain life as we know it. In a major new Afterword for this edition, Behe explains that the complexity discovered by microbiologists has dramatically increased since the book was first published. That complexity is a continuing challenge to Darwinism, and evolutionists have had no success at explaining it. Darwin's Black Box is more important today than ever.Michael J. Behe, a biochemist at Lehigh University, presents here a scientific argument for the existence of God. Examining the evolutionary theory of the origins of life, he can go part of the way with Darwin--he accepts the idea that species have been differentiated by the mechanism of natural selection from a common ancestor. But he thinks that the essential randomness of this process can explain evolutionary development only at the macro level, not at the micro level of his expertise. Within the biochemistry of living cells, he argues, life is "irreducibly complex." This is the last black box to be opened, the end of the road for science. Faced with complexity at this level, Behe suggests that it can only be the product of "intelligent design."  By: Lyle Macwilliam List Price: $24.95 Amazon Price: $16.47 Editorial Review: The NutriSearch Comparative Guide to Nutritional Supplements is your roadmap to understanding the remarkable protective powers of vitamins, minerals, and antioxidants. Packed with the latest findings on inflammation, oxidative stress, and degenerative disease, this guide is the definitive resource for anyone serious about optimal nutrition and anti-aging defence. Inside, you will find over 1,500 US and Canadian supplements scientifically rated and compared, 18 critical Health Support Criteria required to evaluate supplements, 300 full-colour graphs so you can easily compare top-rated products. Discover recent scientific evidence that shows supplements can optimize health and retard the aging process. Determine which supplement is best for you and your family, using a scientifically-based approach. Now in its 4th edition and representing thousands of hours of research, the NutriSearch Comparative Guide to Nutritional Supplements is the way for you to find a quality nutritional supplement that best suits your needs. For those interested in optimizing their health and warding off the aging process, this guide is a must!  By: Steven H. Strogatz List Price: $14.95 Amazon Price: $10.17 Editorial Review: The tendency to synchronize may be the most mysterious and pervasive drive in all of nature. It has intrigued some of the most brilliant minds of the 20th century, including Albert Einstein, Richard Feynman, Norbert Wiener, Brian Josephson, and Arthur Winfree. At once elegant and riveting, Sync tells the story of the dawn of a new science. Steven Strogatz, a leading mathematician in the fields of chaos and complexity theory, explains how enormous systems can synchronize themselves, from the electrons in a superconductor to the pacemaker cells in our hearts. He shows that although these phenomena might seem unrelated on the surface, at a deeper level there is a connection, forged by the unifying power of mathematics. |
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